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KMID : 1123920040180030841
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Korean Journal of Oriental Physiology and Pathology
2004 Volume.18 No. 3 p.841 ~ p.845
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The Effects of Gamcho on Histamine and Cytokine Production In Murine Asthma Model
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Song Sang-Jin
Bae Han-Ho
Park Yang-Chun
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Abstract
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This experiment was designed to investigate the effect of Gamcho(Glycyrrhiza uralensis Fisch, GLU) in asthma. We measured histamine, IL-1β, IL-4, 1L-5, IL-6, IL-10, IL-13, in plasma of ovalbumin induced asthmatic mouse. The results were obtained as follows: GLU decreased the proliferation of histamine, IL-1β, IL-4, IL-5, IL-6, IL-13 significantly. GLU increased the proliferation of IL-10 significantly. According to the above results, it is suggested that GLU extract might be useful applied for prevention and treatment of allergic asthma.
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KEYWORD
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Gamcho, Antiallergy, asthmatic mouse, cytokine
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